Observational study of thrombolytic treatment for acute stroke in patients older and younger than 80 years: experience from one hospital in Bogotá, Colombia, 2007-2014
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Palabras clave

Accidente Cerebrovascular
Terapia Trombolítica
Anciano de 80 o más Años
Factores de Riesgo
Pronóstico

Cómo citar

Bayona-Ortíz, H., Díaz-Cruz, C. A., Góez-Mogollón, L., Useche-Gómez, N., Valencia-Mendoza, M. C., López, V. J., & Díaz-Campos, A. (2017). Observational study of thrombolytic treatment for acute stroke in patients older and younger than 80 years: experience from one hospital in Bogotá, Colombia, 2007-2014. Médicas UIS, 30(3), 21–30. https://doi.org/10.18273/revmed.v30n3-2017002

Resumen

Introducción: describimos la experiencia con el uso de trombólisis para el infarto cerebral isquémico agudo en un centro terciario en América del Sur. Objetivos: describir los principales resultados en nuestra población de pacientes menores y mayores de 80 años tratados con activador recombinante de plasminógeno tisular. Materiales y Métodos: estudio observacional retrospectivo. Se describieron las principales variables y se determinaron los resultados según la edad. Resultados: se incluyeron 70 pacientes. Se encontró que 51,4% eran mujeres y 22,8% eran mayores de 80 años. El tiempo de ventana promedio estuvo en 70 minutos, así como el de puerta-aguja de 90 minutos. La hipertensión, dislipidemia y accidente cerebrovascular previo fueron los factores de riesgo más comunes. En el 25% de los pacientes mayores de 80 años y el 53,7% de los menores de 80 años, tuvieron un resultado favorable en la Escala Modificada de Rankin ≤ 2 (p = 0,009). La mortalidad estuvo presente en el 31,2% de los pacientes mayores de 80 años y en el 5,5% de los pacientes menores de 80 años (p = 0,005). La hemorragia intracerebral sintomática fue de 6,25% en los pacientes mayores de 80 años, frente a los menores de 80 años 3,7% (p = 0,65). Conclusiones: se encontró que la trombólisis todavía presenta beneficio en personas mayores de 80 años. No se encontraron diferencias en cuanto a la hemorragia intra-cerebral sintomática, pero se presentó una mayor mortalidad en los mayores de 80 años. En esta experiencia el uso de rt-PA en la vida real es consistente con otras publicaciones latinoamericanas. MÉD.UIS. 2017;30(3):21-30.

https://doi.org/10.18273/revmed.v30n3-2017002
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