Artículo de Investigación Científica y Tecnológica
Publicado 2017-06-30
Palabras clave
- bioproceso,
- fenomenología,
- empírico,
- explicativo,
- descriptivo
- modelado ...Más
Cómo citar
Ortega Quintana, F. A., Álvarez, H., & Botero castro, H. A. (2017). Enfrentando el modelado de bioprocesos: una revisión de las metodologías de modelado. Revista ION, 30(1). https://doi.org/10.18273/revion.v30n1-2017006
Resumen
En este artículo se presenta una revisión detallada de las diferentes metodologías para el modelado de procesos, señalando sus deficiencias y limitaciones al aplicarlas al modelado de bioprocesos. Como resultado del análisis se encuentra que, al aplicar esas metodologías a los bioprocesos, todas fallan porque no consideran explícitamente la interacción existente entre el medio ambiente y el material celular, al menos de forma descriptiva. Se resalta que hasta ahora la forma de unir estos dos mundos ha sido a través de funciones puramente predictivas. Finalmente, se describen las tendencias en el modelado de bioprocesos, concluyéndose que el enfoque está orientado al planteamiento de modelos matemáticos de base fenomenológica, con rasgos descriptivos o explicativos, para representar la relación existente entre la célula y su medio ambiente.
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