Keywords
Facial transplant
Allogenic transplant
Preoperative period
Postoperative period
Bioethics
Allogenic transplant
Preoperative period
Postoperative period
Bioethics
How to Cite
Méndez-Cárdenas, J. G., Nieto-Fernández, D., Erazo-Arteaga, M. C., Pineda-López, D. M., Quintero-Cuervo, D. Y., Santamaría-Losada, P. A., Ruiz-Moreno, C., Nieto-Bayona, M. A., Leuro-Torres, S. A., & Gómez-Rueda, M. Ángel. (2020). Facial trasplant generalities. Médicas UIS, 33(3), 29–38. https://doi.org/10.18273/revmed.v33n3-2020003
Abstract
The facial transplant is a vascularized compound allogeneic transplant that seeks the reconstruction of massive facial defects allowing the social reintegration of the recipient, generating a positive impact on their quality of life. The objective of this article was to review the literature on generalities of facial transplantation, focusing on the pre, intra and postoperative care regarding the subject. The bibliographic search was performed from September 13, 2018 to March 31, 2019 using the MESH terms “Face Transplant” and “Face Transplantation”. Applying the inclusion and exclusion criteria, 43 articles were obtained on which the review was developed. Facial transplantation is a new procedure in which there are many areas to explore, however, it is a promising alternative to the methods used for the reconstruction of complex facial injuries, which will be optimized as its use expands. MÉD.UIS.2020;33(3): 29-36.
References
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2. Cammarata MJ, Jethanamest D, Rodriguez ED. Otologic considerations in a full face transplant recipient. Laryngoscope.
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3. Topçu Ç, Uysal H, Özkan Ö, Özkan Ö, Polat Ö, Bedeloǧlu M, et al. Recovery of facial expressions using functional electrical stimulation after full-face transplantation. J Neuroeng Rehabil. 2018;15(15):1–7.
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8. Aycart MA, Pomahac B. Discussion. Plast Reconstr Surg [Internet] 2016;138(5):1080–1. Disponible en: https://doi.org/10.1097/ PRS.0000000000002717
9. Lee J. Face transplantation for the blind: more than being blind in a sighted world. J Med Ethics 2018;44(6):361–5.
10. Hashem AM, Hoffman GS, Gastman B, Bernard S, Djohan R, et al. Establishing the Feasibility of Face Transplantation in Granulomatosis With Polyangiitis. Am J Transplant. 2016;16(7):2213–23.
11. Oser ML, Nizzi MC, Zinser JL, Turk M, Epstein R, et al. Quality of Life and Psychosocial Functioning 2 Years Following Facial Transplantation. Psychosomatics [Internet]. 2018;59(6):591–600. Disponible en: https://doi.org/10.1016/j.psym.2018.04.005
12. Cogliandro A, Barone M, Salzillo R, Persichetti P. Quality of Life after Face Transplantation. Plast Reconstr Surg [Internet]. 2017;140(5):757e. Disponible en: https://doi.org/10.1097/PRS.0000000000003818
13. Sosin M, Ceradini DJ, Levine JP, Hazen A, Staffenberg DA, Saadeh PB, et al. Total face, eyelids, ears, scalp, and skeletal subunit transplant: A reconstructive solution for the full face and total scalp burn. Plast Reconstr Surg [Internet]. 2016;138(1):205–19. Disponible en:
ttps://doi.org/10.1097/PRS.0000000000002322
14. Caterson EJ, Diaz-Siso JR, Shetye P, Junker JPE, Bueno EM, et al. Craniofacial principles in face transplantation. J Craniofac Surg. 2012;23(5):1234–8.
15. Sedaghati-nia A, Gilton A, Liger C, Binhas M, Cook F, Ait- Mammar B, et al. Anaesthesia and intensive care management of face transplantation. Br J Anaesth. 2013;111(4):600–6.
16. Diaz-Siso JR, Plana NM, Schleich B, Irving H, Gelb BE, et al. Novel Donor Transfer Algorithm for Multiorgan and Facial Allograft Procurement. Am J Transplant. 2017;17(9):2496–7.
17. Kiwanuka H, Aycart MA, Bueno EM, Alhefzi M, Krezdorn N, Pomahac B. Patient Recruitment and Referral Patterns in Face Transplantation. Plast Reconstr Surg. 2016;138(1):224–31.
18. Tasigiorgos S, Kollar B, Krezdorn N, Bueno EM, Tullius SG, Pomahac B. Face transplantation—current status and future
developments. Transpl Int. 2018;31(7):677–88.
19. Nguyen LL, Naunheim MR, Hevelone ND, Diaz-Siso JR, Hogan JP, Bueno EM, et al. Cost analysis of conventional face reconstructionversus face transplantation for large tissue defects. Plast Reconstr Surg. 2015;135(1):260–7.
20. Shanmugarajah K, Hettiaratchy S, Butler PEM. Facial transplantation. Curr Opin Otolaryngol Head Neck Surg [Internet]. 2012;20(4):291–7. Disponible en: http://content. wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage& an=00020840-201208000-00012
21. Aycart MA, Alhefzi M, Kueckelhaus M, Krezdorn N, Bueno EM, Caterson EJ, et al. A Retrospective Analysis of Secondary Revisions
after Face Transplantation: Assessment of Outcomes, Safety, and Feasibility. Plast Reconstr Surg. 2016;138(4):690e-701e.
22. Pomahac B, Bueno EM, Sisk GC, Pribaz JJ. Current principles of facial allotransplantation: The Brigham and Women’s Hospital
experience. Plast Reconstr Surg. 2013;131(5):1069–76.
23. Diaz-Siso JR, Rodriguez ED. Discussion. Plast Reconstr Surg. 2015;137(1):223e-224e.
24. Marchac A, Kuschner T, Paris J, Picard A, Vazquez MP, Lantieri L. Ethical issues in pediatric face transplantation: Should we perform face transplantation in children? Plast Reconstr Surg.
2. Cammarata MJ, Jethanamest D, Rodriguez ED. Otologic considerations in a full face transplant recipient. Laryngoscope.
2018;129(9): 2008–11.
3. Topçu Ç, Uysal H, Özkan Ö, Özkan Ö, Polat Ö, Bedeloǧlu M, et al. Recovery of facial expressions using functional electrical stimulation after full-face transplantation. J Neuroeng Rehabil. 2018;15(15):1–7.
4. Sweeney N, Allen K, Miller B, Nolan T, Sheerin K. Perioperative Nursing Management of Donor and Recipient Patients Undergoing
Face Transplantation. AORN J [Internet]. 2017;106(1):8–19. Disponible en: http://dx.doi.org/10.1016/j.aorn.2017.05.004
5. Bharadia D, Sinha I, Pomahac B. Role of Facial Vascularized Composite Allotransplantation in Burn Patients. Clin Plast Surg [Internet]. 2017;44(4):857–64. Disponible en: http://dx.doi. org/10.1016/j.cps.2017.05.017
6. Wallins JS, Chandawarkar AA, Dobry A, Diaz-Siso JR, Bueno EM, Caterson EJ, et al. Craniofacial measurements of donors and recipients correlate with aesthetic outcome in virtual face transplantation. Plast Reconstr Surg. 2015;3(5):1–7.
7. Keener AB. Saving face: The search for alternatives to life-long immunosuppression for face transplants. Nat Med [Internet]. 2016;22(5):448–9. Disponible en: http://dx.doi.org/10.1038/ nm0516-448
8. Aycart MA, Pomahac B. Discussion. Plast Reconstr Surg [Internet] 2016;138(5):1080–1. Disponible en: https://doi.org/10.1097/ PRS.0000000000002717
9. Lee J. Face transplantation for the blind: more than being blind in a sighted world. J Med Ethics 2018;44(6):361–5.
10. Hashem AM, Hoffman GS, Gastman B, Bernard S, Djohan R, et al. Establishing the Feasibility of Face Transplantation in Granulomatosis With Polyangiitis. Am J Transplant. 2016;16(7):2213–23.
11. Oser ML, Nizzi MC, Zinser JL, Turk M, Epstein R, et al. Quality of Life and Psychosocial Functioning 2 Years Following Facial Transplantation. Psychosomatics [Internet]. 2018;59(6):591–600. Disponible en: https://doi.org/10.1016/j.psym.2018.04.005
12. Cogliandro A, Barone M, Salzillo R, Persichetti P. Quality of Life after Face Transplantation. Plast Reconstr Surg [Internet]. 2017;140(5):757e. Disponible en: https://doi.org/10.1097/PRS.0000000000003818
13. Sosin M, Ceradini DJ, Levine JP, Hazen A, Staffenberg DA, Saadeh PB, et al. Total face, eyelids, ears, scalp, and skeletal subunit transplant: A reconstructive solution for the full face and total scalp burn. Plast Reconstr Surg [Internet]. 2016;138(1):205–19. Disponible en:
ttps://doi.org/10.1097/PRS.0000000000002322
14. Caterson EJ, Diaz-Siso JR, Shetye P, Junker JPE, Bueno EM, et al. Craniofacial principles in face transplantation. J Craniofac Surg. 2012;23(5):1234–8.
15. Sedaghati-nia A, Gilton A, Liger C, Binhas M, Cook F, Ait- Mammar B, et al. Anaesthesia and intensive care management of face transplantation. Br J Anaesth. 2013;111(4):600–6.
16. Diaz-Siso JR, Plana NM, Schleich B, Irving H, Gelb BE, et al. Novel Donor Transfer Algorithm for Multiorgan and Facial Allograft Procurement. Am J Transplant. 2017;17(9):2496–7.
17. Kiwanuka H, Aycart MA, Bueno EM, Alhefzi M, Krezdorn N, Pomahac B. Patient Recruitment and Referral Patterns in Face Transplantation. Plast Reconstr Surg. 2016;138(1):224–31.
18. Tasigiorgos S, Kollar B, Krezdorn N, Bueno EM, Tullius SG, Pomahac B. Face transplantation—current status and future
developments. Transpl Int. 2018;31(7):677–88.
19. Nguyen LL, Naunheim MR, Hevelone ND, Diaz-Siso JR, Hogan JP, Bueno EM, et al. Cost analysis of conventional face reconstructionversus face transplantation for large tissue defects. Plast Reconstr Surg. 2015;135(1):260–7.
20. Shanmugarajah K, Hettiaratchy S, Butler PEM. Facial transplantation. Curr Opin Otolaryngol Head Neck Surg [Internet]. 2012;20(4):291–7. Disponible en: http://content. wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage& an=00020840-201208000-00012
21. Aycart MA, Alhefzi M, Kueckelhaus M, Krezdorn N, Bueno EM, Caterson EJ, et al. A Retrospective Analysis of Secondary Revisions
after Face Transplantation: Assessment of Outcomes, Safety, and Feasibility. Plast Reconstr Surg. 2016;138(4):690e-701e.
22. Pomahac B, Bueno EM, Sisk GC, Pribaz JJ. Current principles of facial allotransplantation: The Brigham and Women’s Hospital
experience. Plast Reconstr Surg. 2013;131(5):1069–76.
23. Diaz-Siso JR, Rodriguez ED. Discussion. Plast Reconstr Surg. 2015;137(1):223e-224e.
24. Marchac A, Kuschner T, Paris J, Picard A, Vazquez MP, Lantieri L. Ethical issues in pediatric face transplantation: Should we perform face transplantation in children? Plast Reconstr Surg.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2020 Médicas UIS
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