Abstract
Focal nodal hyperplasia is the second most common benign tumor of the liver and should be included in the differential diagnosis of solid liver lesions. We present a case of an adolescent with chronic abdominal pain and abdominal mass finding on physical examination and imaging studies. Surgical resection of the mass was performed, due to the persistent symptoms and uncertainty in diagnosis. We make a literature review on this topic with the objective of known the surgical indications in this pathology. (MÉD. UIS. 2010;23(2):140-3).
Keywords: Focal nodular hyperplasia. Benign liver tumor. Hepatic nodule.
References
1. Wasif N, Sasu S, Conway W, Bilchik A. Focal Nodular Hyperplasia: Report of an Unusual Case and Review of the Literature. The American Surgeon 2008;74:1100-3.
2. International working party. Terminology of nodular hepatocellular lesions. Hepatology 1995;22:983-93.
3. Buscarini E, Danesino C, Plauchu H. High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary hemorrhagic telangiectasia. Ultrasound Med Biol 2004;30:1089-97.
4. Bioulac-Sage P, Rebouissou S, Da Cunha A. Clinical, morphologic, and molecular features defining so-called telangiectatic focal nodular hyperplasias of the liver. Gastroenterology 2005;128:1211-8.
5. Mathieu D, Kobeiter H, Maison P. Oral contraceptive use and focal nodular hyperplasia of the liver. Gastroenterology 2000;118:560-4.
6. Nguyen BN, Flejou JF, Terris B. Focal nodular hiperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol 1999;23:1441-54.
7. Weimann A, Rìnge B, Klempnauer J. Benign liver tumors: differential diagnosis and indication for surgery. World J Surg 1997;21:983-90.
8. Sadowski DC, Lee SS, Wanless IR. Progressive type of focal nodular hyperplasia characterized by multiple tumors and recurrence. Hepatology 1995;61:210-4.
9. Cherqui D, Rahmouni A, Charlotte F. Management of focal nodular hyperplasia and hepatocellular adenoma in young women: a series of 41 patients with clinical, radiological, and pathological correlations. Hepatology 1995;22:1674-81.
10. Lencioni R, Cioni D, Crocetti L. Magnetic resonance imaging of liver tumors. J Hepatol 2004;40:162-71.
11. Kim MJ, Lim HK, Kim SH. Evaluation of hepatic focal nodular hyperplasia with contrast-enhanced gray scale harmonic sonography: initial experience. J Ultrasound Med 2004;23:297-305.
12. Brancatelli G, Federle MP, Grazioli L. Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. Radiology 2001;219:61-8.
13. Grazioli L, Morana G, Federle MP. Focal nodular hyperplasia: morphologic and functional information from MR imaging with gadobenate dimeglumine. Radiology 2001;221:731-9.
14. Ba-Ssalamah A, Schima W, Schmook MT. Atypical focal nodular hyperplasia of the liver: imaging features of nonspecific and liver-specific MR contrast agents. Am J Roentgenol 2002;179:1447-56.
15. Broglia L, Bezzi M, Massa R. Computerized tomography, magnetic resonance, and nuclear medicine in the non-invasive diagnosis of focal nodular hyperplasia of the liver. Radiol Med 1998;96:218-25.
2. International working party. Terminology of nodular hepatocellular lesions. Hepatology 1995;22:983-93.
3. Buscarini E, Danesino C, Plauchu H. High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary hemorrhagic telangiectasia. Ultrasound Med Biol 2004;30:1089-97.
4. Bioulac-Sage P, Rebouissou S, Da Cunha A. Clinical, morphologic, and molecular features defining so-called telangiectatic focal nodular hyperplasias of the liver. Gastroenterology 2005;128:1211-8.
5. Mathieu D, Kobeiter H, Maison P. Oral contraceptive use and focal nodular hyperplasia of the liver. Gastroenterology 2000;118:560-4.
6. Nguyen BN, Flejou JF, Terris B. Focal nodular hiperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol 1999;23:1441-54.
7. Weimann A, Rìnge B, Klempnauer J. Benign liver tumors: differential diagnosis and indication for surgery. World J Surg 1997;21:983-90.
8. Sadowski DC, Lee SS, Wanless IR. Progressive type of focal nodular hyperplasia characterized by multiple tumors and recurrence. Hepatology 1995;61:210-4.
9. Cherqui D, Rahmouni A, Charlotte F. Management of focal nodular hyperplasia and hepatocellular adenoma in young women: a series of 41 patients with clinical, radiological, and pathological correlations. Hepatology 1995;22:1674-81.
10. Lencioni R, Cioni D, Crocetti L. Magnetic resonance imaging of liver tumors. J Hepatol 2004;40:162-71.
11. Kim MJ, Lim HK, Kim SH. Evaluation of hepatic focal nodular hyperplasia with contrast-enhanced gray scale harmonic sonography: initial experience. J Ultrasound Med 2004;23:297-305.
12. Brancatelli G, Federle MP, Grazioli L. Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. Radiology 2001;219:61-8.
13. Grazioli L, Morana G, Federle MP. Focal nodular hyperplasia: morphologic and functional information from MR imaging with gadobenate dimeglumine. Radiology 2001;221:731-9.
14. Ba-Ssalamah A, Schima W, Schmook MT. Atypical focal nodular hyperplasia of the liver: imaging features of nonspecific and liver-specific MR contrast agents. Am J Roentgenol 2002;179:1447-56.
15. Broglia L, Bezzi M, Massa R. Computerized tomography, magnetic resonance, and nuclear medicine in the non-invasive diagnosis of focal nodular hyperplasia of the liver. Radiol Med 1998;96:218-25.
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