Abstract
Nitric oxide is a multifunctional regulator, which is central to diverse processes including infammation, vasoregulation, intra-and intercellular signaling, apoptosis, and carcinogenesis. The failure in the synthesis and/or loss of bioavailability of nitric oxide is the main characteristic of many diseases. Understanding the mechanisms underlying the effects of nitric oxide at the cellular and tissue level, will allow the development of new therapies to balance the effects of nitric oxide in vivo. The purpose of this review is to mention the key findings in the feld of research on this diatomic gas and their biological dynamics.
Key words: Antioxidant. Radical nitrogen species. Radical oxygen species. Nitric oxide. Cell signalling.
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