Abstract
Introduction: Trauma is a public health problem in Colombia and is the first cause of death in young people with an incidence rate of 331.99 cases per 100 000 inhabitants, of which approximately 30% die in the intensive care unit. These patients according to their severity will require stabilization of vital signs and close monitoring which includes the acid-base status. Objetive: To establish the relationship between outcome and variables of acid-base equilibrium of those patients diagnosed with trauma in the intensive care unit of the Hospital Universitario San Jorge in Pereira, Colombia. Materials and Methods: A prospective cohort study in type was performed on the intensive care unit with general trauma patients who were taking blood gases on admission to the unit and were monitored over time until discharge. Results: The population of the study were 38 patients with trauma, 68.4% were men. Average age was 35±19 years and 18.4% of patients admitted died. The univariate analysis was found individual relationship with outcome and variables such as sodium, arterial oxygen saturation, alveolar oxygen pressure and APACHE II score. In the Cox regression model it was found a relationship between outcome and variables such as alveolar oxygen pressure, pressure oxygen pressure, heart rate and arterial-alveolar ratio of oxygen. Conclusion: Variables found that alveolar oxygen pressure, arterial oxygen pressure, heart rate and arterial-alveolar oxygen ratio of arterial blood gas analysis, correlate with survival of patients in critical condition. An invitation to use this paraclinical test is done. MÉD UIS. 2015;28(3):273-80.
References
León HE. Aspectos epidemiológicos del trauma en Colombia. Arch med. 2004;4(9):55-62.
Instituto Nacional de Medicina Legal y Ciencias Forenses. Forensis Datos para la vida. Bogotá: Grupo Centro de Referencia Nacional sobre Violencia [actualizada en junio de 2012: consultada el 24 de Noviembre de 2012]. Disponible en: http://
www.medicinalegal.gov.co/forensis .
Instituto Nacional de Medicina Legal y Ciencias Forenses. Forensis Datos para la vida. Bogotá: Grupo Centro de Referencia Nacional sobre Violencia [actualizada en julio de 2014: consultada el 25 de Mayo de 2015]. Disponible en: http://www.
medicinalegal.gov.co/forensis .
Instituto Nacional de Medicina Legal y Ciencias Forenses Regional Occidente. Violencia y accidentalidad en Risaralda. Pereira: Grupo Centro de Referencia Regional sobre Violencia [actualizada en junio de 2011: consultada el 24 de Noviembre de 2012]. Disponible en: http://www.medicinalegal.gov.co/
violencia-y-accidentalidad-risaralda .
Shere-Wolfe RF, Galvagno SM, Grissom TE. Critical care considerations in the management of the trauma patient following initial resuscitation. Scand J Trauma Resusc Emerg Med. 2012;20:68.
Huang YC. Monitoring oxygen delivery in the critically Il. Chest. 2005;128(5 Suppl 2):554S-60.
Gem Premier 3000 Manual.
Edwards SL. Pathophysiology of acid base balance: The theory practice relationship. Intensive Crit Care Nurs. 2008; 24(1):28-38.
Smith-Erichsen N, Kofstad J, Ingvaldsen B. Acid-base disturbances in intensive care patients. Tidsskr Nor Laegeforen. 2010; 130(15):1471-4.
Baylis C, Till C. Interpretation of arterial blood gases. Surg (Oxford). 2009;27(11):470-4.
Aristizábal-Salazar RE, Calvo-Torres LF, Valencia-Arango LA, Montoya-Cañón M, Barbosa-Gantiva O, Hincapié-Baena V. Equilibrio Ácido-Base: el mejor enfoque clínico. Rev Colomb Anestesiol. 2015;43:219-24.
Park M, Maciel AT, Noritomi DT, Pontes de Azevedo LC, Taniguchi LU, daCruz Neto LM. Effect of PaCo2 variation on standard base excess value in critically ill patients. J Crit Care. 2009; 24(4):484-91.
Morgan TJ. Invited commentary: Putting standard base excess to the test. J Crit Care. 2009; 24(4):492-3.
Kofstad J. Base excess: a historical review-has the calculation of base excess been more standardized the last 20 years? Clin Chim Acta. 2001; 307(1–2):193-5.
Mentel A, Bach F, Schüler J, Herrmann W, Koster A, Crystal GJ, et al. Assessing Errors in the Determination of Base Excess. Anesth Analg. 2002; 94(5):1141-8.
Greenbaum J, Nirmalan M. Acid–base balance: The traditional approach. Curr Anesth Crit Care. 2005; 16(3):137-42.
Kratz A, Ferraro M, Sluss PM, Lewandrowski KB. Normal Reference Laboratory Values. N Engl J Med. 2004; 351(15):1548-63. 1. Karbing D, Kjaergaard SR, Smith B, Espersen K, Allerod C, Andreassen S, Rees S. Variation in the PaO2/FiO2 ratio with
FiO2: mathematical and experimental description, and clinical relevance. Crit Care. 2007; 11(6):R118
Karbing D, Kjaergaard SR, Smith B, Espersen K, Allerod C, Andreassen S, Rees S. Variation in the PaO2/FiO2 ratio with FiO2: mathematical and experimental description, and clinical relevance. Crit Care. 2007; 11(6):R118.
Berg MJ, Fynbo C, Christiansen S, Jensen R, Lemeshow S. Comparison of Charlson comorbidity index with sAPs and APACHE scores for prediction of mortality following intensive care. Clin Epidemiol. 2011; 3: 203–11.
Quach S, Hennessy DA, Faris P, Fong A, Quan H, Doig C. A comparison between the APACHE II and Charlson Index Score for predicting hospital mortality in critically ill patients. BMC Health Serv Res. 2009; 9:129.
Dossett LA, Redhage LA, Sawyer RG, May AK. Revisiting the Validity of APACHE II in the Trauma ICU: Improved Risk Stratification in Critically Injured. Injury. 2009; 40(9):993-8.
Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985; 13(10):818-29.
Chalya PL, Gilyoma JM, Dass RM, Mchembe MD, Matasha M, Mabula JB, et al. Trauma admissions to the intensive care unit at a reference hospital in Northwestern Tanzania. Scand J Trauma Resusc Emerg Med. 2011; 19:61.
Raum MR, Nijsten MW, Vogelzang M, Schuring F, Lefering R, Bouillon B, et al. Emergency trauma score: An instrument for early estimation of trauma severity. Crit Care Med. 2009; 37 (6): 1972-7.
Aristizábal RE, Martínez JW, Montoya M, Barbosa O, Calvo LF, Valencia LA, et al. Relación del aporte de oxígeno y la supervivencia del paciente con shock en UCI. Investigaciones Andinas. 2012;14 (25):588-600.
Vincent JL, Opal SM, Marshall JC. Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions. Crit Care Med. 2010; 38(1):283-7.
Nguyen HB,Van Ginkel C,Batech M,Banta J, Corbett SW. Comparison of Predisposition, Insult/Infection, Response, Organ dysfunction, Acute Physiology And Chronic Health Evaluation II, and Mortality in Emergency Department Sepsis
inpatients meeting criteria for early goal-directed therapy and the severe sepsis resuscitation bundle. J Crit Care. 2011; 27(4):362-9.
Wenner JB, Norena M, Khan N, Palepu A, Ayas NT, Wong H, et al. Reliability of intensive care unit admitting and comorbid diagnoses, race, elements of Acute Physiology and Chronic Health Evaluation II score, and predicted probability of
mortality in an electronic intensive care unit database. J Crit Care. 2009; 24(3)401-7.