Necrólisis epidérmica tóxica asociada a anticonvulsivantes. Presentación de un caso en el Hospital Universitario de Santander, Bucaramanga, Colombia
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Mantilla, J. C., Pico-Espinosa, O. J., Forero Naranjo, L. F., Tapias, D. L., Mahecha Castro, N. M., & Uribe Herrera, N. (2009). Necrólisis epidérmica tóxica asociada a anticonvulsivantes. Presentación de un caso en el Hospital Universitario de Santander, Bucaramanga, Colombia. Médicas UIS, 22(3). Retrieved from https://revistas.uis.edu.co/index.php/revistamedicasuis/article/view/800

Abstract

 

Toxic epidermal necrolysis is an infrequent pathology, accompanied of high mortality risk in concordance with extension of comprised skin characterized for blisters. Frequently these are present in respiratory, digestive and ocular mucous. An autopsy case is presented occurred in Hospital Universitario de Santander in october 2007 of toxic epidermal necrolysis secondary to treatment with phenytoin associated with valproic acid as anticonvulsivant therapy for messial hippocampal sclerosis. It pretends with this work show a review and to analyze related factors with this condition.  

Key words: Toxic epidermal necrolysis. Stevens Johnson Syndrome. Phenytoin. Hippocampal sclerosis. Autopsy.

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