Coagulación intravascular diseminada

  • Jesús Daniel Mogollón Gallo Universidad Pedagógica y Tecnológica de Colombia. Tunja. Colombia
  • Meike Katheleen Merchán Figueroa Universidad Pedagógica y Tecnológica de Colombia - UPTC. Tunja, Colombia
  • Carlos Andrés Gualdrón Frías Universidad Pedagógica y Tecnológica de Colombia - UPTC. Tunja, Colombia.
  • Paula Andrea Parra Pinzón Universidad Pedagógica y Tecnológica de Colombia - UPTC. Tunja, Colombia.
  • Diana Patricia Niño Rodríguez Universidad Pedagógica y Tecnológica de Colombia. Tunja. Colombia
  • Vicky Johanna Obando Bustos Universidad Nacional de Colombia. Bogotá D.C. Colombia.

Resumen

La coagulación intravascular diseminada es un estado alterado de la coagulación secundario a cuadros inflamatorios locales o sistémicos. Se caracteriza por un aumento de la coagulación y una inadecuada fibrinólisis endógena que da como resultado la formación de fibrina intravascular, trombosis microvascular multiorgánica y un excesivo consumo de los factores de coagulación sanguínea, esto desencadena sangrados severos y trombosis, los cuales conducen a falla orgánica y circulatoria como principal manifestación clínica. Este artículo tiene como objetivo realizar una revisión del estado del arte describiendo su definición, etiología, fisiopatología, manifestaciones clínicas y actualidades en su diagnóstico y tratamiento. Para esto, se realizó una búsqueda bibliográfica en PubMed utilizando el término MeSH “Disseminated Intravascular Coagulation”, seleccionándose 63 artículos por la relevancia y pertinencia de su información al objetivo de la investigación. De esta manera, se espera brindar al clínico las herramientas necesarias para responder adecuadamente frente a esta patología. MÉD.UIS.2020;33(2):75-84.

Palabras clave: Coagulación Intravascular Diseminada, Trombina, Fibrinólisis, Hemorragia, Trombosis

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Publicado
2020-10-26
Sección
Revisión de tema