Complicaciones endocrinológicas del síndrome de Down en pediatría: revisión de la literatura
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Palabras clave

Síndrome de Down
Enfermedades del Sistema Endocrino
Hormonas Tiroideas
Diabetes Mellitus
Crecimiento
Obesidad
Pubertad
Fertilidad
Trastornos del Metabolismo de los Lípidos
Pediatría

Cómo citar

Sarmiento, M. P., & Gómez, S. (2022). Complicaciones endocrinológicas del síndrome de Down en pediatría: revisión de la literatura. Médicas UIS, 35(3), 91–103. https://doi.org/10.18273/revmed.v35n3-2022010

Resumen

El síndrome de Down constituye la cromosopatía más frecuente a nivel mundial y afecta 6,03 a 7,86 de cada 10.000 nacidos vivos en Colombia. Los pacientes pediátricos de este grupo poblacional presentan una mayor incidencia de complicaciones endocrinológicas comparados con la población general. El objetivo de este artículo es revisar las complicaciones endocrinológicas prevalentes en el paciente pediátrico con síndrome de Down, relacionadas con el hipocrecimiento, desarrollo puberal, patología tiroidea, diabetes mellitus, dislipidemias y obesidad; así como describir su seguimiento y tratamiento. Se realizó una búsqueda en la literatura desde agosto de 2020 hasta diciembre de 2021, en las bases de datos PubMed y Google Scholar; incluyendo un total de 44 publicaciones para la presente revisión. Se concluye que el paciente pediátrico con síndrome de Down evidencia un patrón de hipocrecimiento junto a un mayor riesgo de obesidad y sobrepeso. Adicionalmente, presenta con mayor frecuencia patología tiroidea y diabetes mellitus.

https://doi.org/10.18273/revmed.v35n3-2022010
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