Hemorragia alveolar difusa en paciente con trombocitopenia inmune primaria refractaria: reporte de caso
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Palabras clave

Hemoptisis
Lavado broncoalveolar
Barrera alveolocapilar
Trombocitopenia
Autoinmunidad

Cómo citar

Rondón Carvajal, J., Álvarez López, S., & Escudero Correa, M. J. (2024). Hemorragia alveolar difusa en paciente con trombocitopenia inmune primaria refractaria: reporte de caso. Médicas UIS, 37(1), 121–131. https://doi.org/10.18273/revmed.v37n1-2024010

Resumen

La hemorragia alveolar difusa, manifestación de varias enfermedades de estirpe inmune y no inmune, constituye una rara complicación de la trombocitopenia autoinmune primaria. Se considera en pacientes con disnea, opacidades alveolares en imágenes torácicas y presencia de más de 20 % de macrófagos cargados de hemosiderina en lavado broncoalveolar. Se presenta el caso de una mujer con diagnóstico conocido de trombocitopenia inmune primaria, remitida de consulta externa por recuento plaquetario menor de 10 000 plaquetas/mililitro, quien cursó con hipoxemia de rápida instauración, opacidades en vidrio esmerilado y lavado broncoalveolar con gran cantidad de macrófagos cargados de hemosiderina, configurando el diagnóstico de hemorragia alveolar, que respondió a terapia citostática combinada en términos de mejoría sostenida en el recuento plaquetario. Se aduce la importancia de identificar elementos de juicio clínico que permitan lograr un diagnóstico temprano, así como establecer puentes transdisciplinarios que conduzcan a un tratamiento efectivo en un escenario potencialmente fatal.

https://doi.org/10.18273/revmed.v37n1-2024010
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