Keywords
Aged
Social Class
Inappropriate Prescribing
Prevalence
Sickness Impact
Epidemiologic Factors
Medication Errors
Comorbidity
Frailty
How to Cite
Abstract
Introduction: Polypharmacy and inappropriate prescribing have been related to multiple variables, including sociodemographic, however the evidence is limited and heterogeneous. Objective: To evaluate the association between polypharmacy and inappropriate prescribing in adults over 60 years old according to their social class. Material and methods: A pilot cross-sectional population-based study in the city of Bucaramanga, Colombia, with a sample of 135 adults over 60 years old. A survey was conducted where sociodemographics, health status in the last month, comorbidities, drugs of chronic use and functionality according to scales were registered. Results: No statistical association was found between inappropriate prescribing and Polypharmacy amongst social class and education level (P=0.639). Nevertheless, having an affiliation with a subsidized social security system was significantly associated with infra prescription (P <0.029). The existence of monthly income was associated with the presence of polypharmacy (P <0.029) and inadequate prescribing (P <0.033). Conclusions: There exists an association between some socioeconomic variables, the number of practicing physicians and some medical specialties with polypharmacy and inadequate prescription of drugs.
References
Ministerio de Salud y Protección Social. Envejecimiento Demográfico. Colombia 1951- 2020. Dinámica Demográfica Y Estructuras Poblacionales. 2013; 48.
Higuera, C. A., Elsharkawy, K., Klika, A. K., Brocone, M., & Barsoum WK, Prevention D, Promotion H, Health P. The State of Aging and Health in America 2013 is the sixth volume of a series that presents a snapshot of the health and aging landscape in the United States or another region of the world. This series presents the most current information and statistics. Clin Orthop Relat Res. 2013; 469(5): 1391-1400.
Gnjidic D, Hilmer SN, Blyth FM, Naganathan V, Waite L, Seibel MJ, et al. Polypharmacy cutoff and outcomes: Five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes. J Clin Epidemiol. 2012; 65(9): 989-995. doi: http://dx.doi.org/10.1016/j.jclinepi.2012.02.018
Onder G, Petrovic M, Tangiisuran B, Meinardi MC, Markito-Notenboom WP, Somers A, et al. Development and validation of a score to assess risk of adverse drug reactions among in-hospital patients 65 years or older. Arch Intern Med. 2010; 170(13): 1142-1148. doi: 10.1001/archinternmed.2010.153
Gurwitz JH. Neither Too Much nor Too Little. 1999; 281(2): 113-115.
Thomas HF, Sweetnam PM, Janchawee B, Luscombe DK. Polypharmacy among older men in South Wales. Eur J Clin Pharmacol. 1999; 55(5): 411-415.
Gokce Kutsal Y, Barak A, Atalay A, Baydar T, Kucukoglu S, Tuncer T, et al. Polypharmacy in the elderly: A multicenter study. J Am Med Dir Assoc. 2009; 10(7): 486-490.
Passi A, Margozzini P, Valenzuela E, Hoyl T, Marín PP, Carrasco M, et al. Uso inapropiado de medicamentos en adultos mayores: resultados de la Encuesta Nacional de Salud 2010. Rev Med Chil. 2016; 144(4): 417-425.
Marzi MM, Diruscio V, Nunez HM, Pires SM, Quaglia BN. Analysis of medication prescription in an Argentinian geriatric hospital. Rev Med Chil. 2013; 141(2): 194-201.
Cano-Gutierrez C, Samper-Ternent R, Cabrera J, Rosselli D. Medication use among older adults in Bogota, Colombia. Rev Peru Med Exp Salud Publica. 2016; 33(3): 419-424.
Holguín-Hernández E, Orozco-Díaz JG. Medicación potencialmente inapropiada en ancianos en un hospital de primer nivel, Bogotá 2007. Rev Salud Pública. 2010; 12(2): 287-299.
Gurwitz JH, Field TS, Harrold LR, Rothschild J, Debellis K, Seger AC, et al. Incidence and preventability of in the ambulatory setting. J Am Med Assoc. 2003; 289(9): 1107-1116.
Shah BM, Hajjar ER. Polypharmacy, adverse drug reactions, and geriatric syndromes. Clin Geriatr Med. 2012; 28(2): 173-186. doi: http://dx.doi.org/10.1016/j.cger.2012.01.002
Castro-Rodríguez J, Orozco-Hernández JP M-MD. Polifarmacia y prescripción de medicamentos potencialmente no apropiados en ancianos. Rev Méd Risaralda. 2016; 22(1): 52-57.
Solís C, Arrioja S, Manzano A. Índice de Barthel (IB): Un instrumento esencial para la evaluación funcional y la rehabilitación. 2005; 4: 1-6.
Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969; 9(3): 179-186. doi: https://doi.org/10.1093/geront/9.3_Part_1.179
Charlson ME, Pompei P, Ales KL, MacKenzie R. A new method of classifying prognostic in longitudinal studies: development and validation. J Chronic Diseases. 1987; 40: 373-383.
Cabrera D, Menenedez A, Fernandez A, Acebal V, Garcia J. Evaluación de la fiabilidad y validez de una escala de valoración social en el anciano Evaluation of the reliability and validity of a scale of social evaluation of the elderly. 1996; 1-9.
Rosselli D, Ardila A, Pradilla G, Morillo L, Bautista L, Rey O, et al. The Mini-mental state examination as a selected diagnostic test for dementia: a Colombian population study. GENECO. Rev Neurol. 1999; 30(5): 428-432.
Delgado Silveira E, Muñoz García M, Montero Errasquin B, Sánchez Castellano C, Gallagher PF, Cruz-Jentoft AJ. Prescripción inapropiada de medicamentos en los pacientes mayores: los criterios STOPP/START. Rev Esp Geriatr Gerontol. 2009; 44(5): 273-279.
Woo J, Zheng Z, Leung J, Chan P. Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics. BMC Geriatr. 2015; 15(1): 1-11. doi: http://dx.doi.org/10.1186/s12877-015-0160-7
Haider SI, Johnell K, Thorslund M, Fastbom J. Analysis of the association between polypharmacy and socioeconomic position among elderly aged ≥77 years in Sweden. Clin Ther. 2008; 30(2): 419-427.
Corsonello A, Pedone C, Corica F, Incalzi RA. Polypharmacy in elderly patients at discharge from the acute care hospital. Ther Clin Risk Manag. 2007; 3(1): 197-203.
Vyas A, Pan X, Sambamoorthi U. Chronic condition clusters and polypharmacy among adults. Int J Family Med. 2012; 2012: 1-8.
Ascar GI, Hespe CB, Hernández MM. Relación entre polifarmacia y número de médicos consultados por pacientes ancianos. Rev Cuba Farm. 2015; 49(3): 491-501.
Mosegui GBG, Rozenfeld S, Veras RP, Vianna CMM. Avaliação da qualidade do uso de medicamentos em idosos. Rev Saude Publica. 1999; 33(5): 437-444.
Arey LB, Tremaine MJ, Monzingo FL. The numerical and topographical relations of taste buds to human circumv allate papillae throughout the life span. Anat Rec. 1935; 64(1): 9-25.
Lutz BH, Miranda VIA, Bertoldi AD. Potentially inappropriate medications among older adults in Pelotas, Southern Brazil. Rev Saude Publica. 2017; 51(0): 1-12.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2021 Maria José Albarracín Ruiz, Silvia Juliana Bueno-Florez, Carlos Eduardo Rodríguez-Bohorquez, Angie Lorena Blanco-Guarín, Miguel Oswaldo Cadena-Sanabria