Abstract
Methicillin-resistant Staphylococcus aureus is an isolated germ mainly in hospital settings. However, this condition has changed in the last years. Today, it is recognized as a germ that causes infections acquired in the community by children, without predisposing risk factors. This may vary around the world, but there is a global alert for the increase of the problem. In Latin America, this has already been reported in some countries such as Argentina and Colombia. Evaluating the circulating germs at regional level and their genotypic characteristics is important for the clinical management of some patients, including children under a year of age as they are also susceptible to this infection. We are presenting two cases in children under one year of age, including a neonate, which are a susceptible age group. The clinical suspicion of this acquisition bacteria in the community helps the adequate choice of the antibiotic scheme, with better clinical outcomes. Therefore, it must be a priority to carry out the local surveillance of Staphylococcus aureus infections acquired in the Community and determine the management
protocols, according to age groups and associated conditions.
References
García Apac C. Community-acquired methicillinresistant Staphylococcus aureus infection. Acta Med Per. 2011; 28(2): 159-162.
Gentile A, Bakir J, Ensinck G, Cancellara A, Casanueva EV, Firpo V et al. Communityacquired methicillin resistant Staphylococcus aureus infections: hospitalization and case fatality risk in 10 pediatric facilities in Argentina. Arch Argent Pediatr. 2018; 116(1): e47-e53. doi: 10.5546/aap.2018.eng.e47
de Sousa E, de Oliveira AC. Community-acquired methicillin-resistant Staphylococcus aureus: a global problem. Rev Bras Enferm. 2015; 68(1): 136-143. doi: https://doi.org/10.1590/0034-7167.2015680119i
Ensinck G, Ernst A, Lazarte G, Romagnoli A, Sguassero Y, Míguez N et al Community-acquired methicillin-resistant Staphylococcus aureus infections: 10-years’ experience in a children’s hospital in the city of Rosario, Argentina. Arch Argent Pediatr. 2018; 116(2): 119-125. doi: 10.5546/aap.2018.eng.119
Salazar-Ospina L, Jiménez JN. High frequency of methicillin-susceptible and methicillinresistant Staphylococcus aureus in children under 1 year old with skin and soft tissue infections. J Pediatr (Rio J). 2018; 94(4): 380-389. doi: 10.1016/j.jped.2017.06.020
Junie LM, Jeican II, Matroş L, Pandrea SL. Molecular epidemiology of the communityassociated methicillin-resistant staphylococcus aureus clones: a synthetic review. Clujul Med. 2018; 91(1): 7-11. doi: 10.15386/cjmed-807
Lim WH, Lien R, Huang YC, Lee WJ, Lai JY. Community associated methicillineus necrotizing pneumonia in a healthy neonate. J Microbiol Immunol Infect. 2014; 47(6): 555-557. doi: 10.1016/j.jmii.2012.07.001
Frick MA, Moraga-Llop FA, Bartolomé R, Larrosa N, Campins M, Roman Y et al. Community acquired methicillin-resistant Staphylococcus aureus infections in children. Enferm Infecc Microbiol Clin. 2010; 28(10): 675-679. doi: 10.1016/j.eimc.2010.01.007
VanEperen AS, Segreti J. Empirical therapy in Methicillin-resistant Staphylococcus Aureus infections: An Up-To-Date approach. J Infect Chemother. 2016; 22(6): 351-9. doi: 10.1016/j.jiac.2016.02.012
Galli L, Venturini E, Bassi A et al. Common Community-acquired Bacterial Skin and Softtissue Infections in Children: An Intersociety Consensus on Impetigo, Abscess, and Cellulitis Treatment. Clin Ther. 2019; 41(3): 532-551. doi: 10.1016/j.clinthera.2019.01.010
Moreno-Pérez D, Andrés Martín A, Tagarro García A, Escribano Montaner A, Figuerola Mulet J, García García JJ et al. Community acquired pneumonia in children: Treatment of complicated cases and risk patients. Consensus statement by the Spanish Society of Paediatric Infectious Diseases (SEIP) and the Spanish Society of Paediatric Chest Diseases (SENP). An Pediatr (Barc). 2015; 83(3): 217.e1-11. doi: 10.1016/j.anpedi.2014.12.002
Khamash DF, Voskertchian A, Tamma PD, Akinboyo IC, Carroll KC, Milstone AM. Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections. J Pediatric Infect Dis Soc. 2019; 25; 8: 351-353. doi: 10.1093/jpids/piy062
Khalid M, Junejo S, Mir F. Invasive Community Acquired Methicillin-Resistant Staphylococcal Aureus (CA-MRSA) Infections in Children. J Coll Physicians Surg Pak. 2018; 28(9): S174-S177. doi: 10.29271/jcpsp.2018.09.S174
Marhuenda C, Barceló C, Fuentes I, Guillén G, Cano I, López M et al. Urokinase versus VATS for treatment of empyema: a randomized multicenter clinical trial. Pediatrics. 2014; 134(5): e1301-1307. doi: 10.1542/peds.2013-3935
Chen J, Luo Y, Zhang S, Liang Z, Wang Y, Zhang Y et al. Community-acquired necrotizing pneumonia caused by methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a Chinese teenager: case report and literature review. Int J Infect Dis. 2014; 26: 17-21. doi: 10.1016/j.ijid.2014.02.025
Machuca MA, González CI, Sosa LM. Methicillinresistant Staphylococcus aureus causes both community-associated and health care-associated infections in children at the Hospital Universitario de Santander. Biomedica. 2014; 34 Suppl 1: 163-169. doi: 10.1590/S0120-41572014000500019
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