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Abstract
Introduction: For an adequate protection of human health, especially in populations of pregnant women and vulnerable children, it is necessary to accurately estimate the risks in the health effects of pesticide exposure. Objective: To identify articles selected from an electronic search of PubMed and Science Direct databases that have linked the effects of pesticides with health problems in pregnant women and their newborns. Introduction: For an adequate protection of human health, especially in populations of pregnant women and vulnerable children, it is necessary to accurately estimate the risks in the health effects of pesticide exposure. Objective: To identify articles selected from an electronic search of PubMed and Science Direct databases that have linked the effects of pesticides with health problems in pregnant women and their newborns. Methods: In this review, we characterized epidemiological studies that evaluate health effects from exposure to pesticides, especially organophosphates (OPs) and organochlorines (OCs). Also analyzed were studies in which exposure assessments are performed in pregnant women living in agricultural areas, men with occupational exposure, children born and residing in areas where pesticides are used, studies associated pesticide use with cytogenetic abnormalities in newborns, DNA damage, and adverse birth effects from pesticide exposure. Results: some results of the studies provided evidence to support the hypothesis that pesticide exposure is negatively associated with effects on the quality of life of children whose parents are exposed to pesticides, since children are exposed to different levels of pesticides during pregnancy, birth, and growth. Conclusion: The validity of the reviewed epidemiological and scientific studies is strongly enhanced by exposure assessment based on quantification of molecular biomarkers.
References
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