Como Citar
Resumo
La alopecia areata es una enfermedad autoinmune que genera la caída del pelo de forma no-cicatrizante. El estrés
psicológico es uno de los factores que pueden contribuir en su etiopatogenia al incrementar las concentraciones de la hormona liberadora de corticotropina, la cual genera un ambiente altamente inflamatorio y la pérdida del privilegio
inmune alrededor del folículo piloso. Presentación del caso: Mujer de 37 años con antecedente de alopecia areata, quien presenta pérdida progresiva del pelo después del anuncio de un embarazo gemelar, el cual le desencadena un nivel de estrés psicológico considerable. El examen físico evidencia ausencia de pelo en toda la superficie corporal. Terminada la lactancia, se inicia manejo con corticoides tópicos y tofacitinib (inhibidor de las janus kinasa) con el cual consigue recuperar el pelo capilar y corporal. Dentro de los factores medioambientales, que pueden contribuir al desarrollo de Alopecia Areata, el estrés es uno de los más importantes. Por ende, conocer la fisiopatología del estrés permite entender cómo este factor ambiental dispara la aparición de enfermedades autoinmunes y por qué terapias como los inhibidores de las janus kinasas son útiles en su tratamiento.
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Copyright (c) 2022 Angelica María González-Clavijo, Johiner Jahir Vanegas-Antolinez, Heitmar-Santiago Infante-Fernández, Katerine Quintero-Martínez, Sebastián Parrado-García, Santiago Piñeros-Cortés, Camilo Ochoa-Abella