Abstract
As the different problems that exist when carrying out implant procedures due to the quality of the bone remnant
and the state of the existing periodontal tissues in the area to be rehabilitated, there are induced bone regeneration
options that show considerably favorable success rates as they are used in cases where extensive bone regeneration
is necessary to support a dental implant. The objective of the present study is to describe the success in bone
regeneration using combined alternatives of platelet-rich fibrin and biological modification with tetracycline.
Report of the clinical case: 67-year-old female patient consulted for inflammation and suppuration and pain in the upper antero-superior area, she was diagnosed as chronic periapical abscess, dental organ extraction surgery was performed, after that decontamination and adaptation of the alveoli was performed with tetracycline to perform
guided bone regeneration with platelet-rich fibrin, Coat membrane and Lumina bone criteria, then wait for the
evolution process to place dental implants. The success obtained with the use of FRP and bone biomodification as
an adjuvant in the disinfection of the area to be treated achieved to show highly favorable results in the guided bone regeneration process.
References
Acosta AP, Gutiérrez SJ, Bedoya MA, García DA, Moreno XE. Evaluación del efecto del plasma rico en plaquetas en diferentes tiempos y concentraciones sobre la viabilidad de fibroblastos de ligamento periodontal y osteoblastos. Universitas Odontol. 2017; 36(76). doi: https://doi.org/10.11144/Javeriana.uo36-76.eepr
Del Rio D, Romero A, Díaz Caballero AJ. Biomodificación alveolar como un procedimiento indispensable previo a regeneración ósea guiada. Rev Cubana Estomatol. 2020; 57(3): e2083. http://www.revestomatologia.sld.cu/index.php/est/article/view/2083/1797
Strauss FJ, Stähli A, Gruber R. The use of plateletrich fibrin to enhance the outcomes of implant therapy: A systematic review. Clin Oral Implants Res. 2018; 29(Suppl 18): 6-19. doi: https://doi.org/10.1111/clr.13275
Liu Y, Sun X, Yu J, Wang J, Zhai P, Chen S, Liu M, Zhou Y. Platelet-Rich fibrin as a bone graft material in oral and maxillofacial bone regeneration: Classification and summary for better application. Biomed Res Int. 2019; 2019:3295756. doi: https://doi.org/10.1155/2019/3295756
Cruz-Molina C, Castro-Rodríguez Y. Resultados de los concentrados plaquetarios en la regeneración ósea guiada. Rev Cub Invest Biomédicas. 2020; 39(2): e515.
Zumarán CC, Parra MV, Olate SA, Fernández EG, Muñoz FT, Haidar ZS. The 3 R’s for platelet-rich fibrin: A «Super» tri-dimensional biomaterial for contemporary naturally-guided oro-maxillo-facial soft and hard tissue repair, reconstruction and regeneration. Materials (Basel). 2018; 11(8): 1293. doi: https://doi.org/10.3390/ma11081293
García García V, Corral I, Bascones Martínez A. Plasma Rico en Plaquetas y su utilización en implantología dental. Av Periodon Implantol. 2004; 16(2): 81-92.
López-Pagán E, Pascual Serna AC. Fibrina rica en plaquetas en la cicatrización de los tejidos periodontales. Odontol Sanmarquina. 2020; 23(1): 743-50. doi: https://doi.org/10.15381/os.v23i1.17506
Lei L, Yu Y, Ke T, Sun W, Chen L. The application of three-dimensional printing model and plateletrich fibrin technology in guided tissue regeneration surgery for severe bone defects. J Oral Implantol. 2019; 45(1): 35-43. doi: https://doi.org/10.1563/aaid-joi-D-17-00231
Trobos M, Juhlin A, Shah F, Hoffman M, Sahlin H, Dahlin C. In vitro evaluation of barrier function against oral bacteria of dense and expanded polytetrafluoroethylene (PTFE) membranes for guided bone regeneration. Clin Implant Dent Relat Res. 2018; 20(5): 738-748. doi: https://doi.org/10.1111/cid.12629
Alzahrani AA, Murriky A, Shafik S. Influence of platelet rich fibrin on post-extraction socket healing: A clinical and radiographic study. Saudi Dent J. 2017; 29(4): 149-155. doi: https://doi.org/10.1016/j.sdentj.2017.07.003
Nuñez-Muñoz MA, Castro-Rodríguez Y. Resultados del uso de la fibrina rica en plaquetas y rellenos óseos en la regeneración ósea guiada. Revisión sistemática. Rev Esp Cirug Oral Maxilof. 2019; 41(3): 126-137. doi: https://dx.doi.org/10.20986/recom.2019.1032/2019
Golub LM, Lee HM. Periodontal therapeutics: Current host-modulation agents and future directions. Periodontol 2000. 2020; 82(1):186-204. doi: 10.1111/prd.12315
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2022 Víctor Simancas-Escorcia, Astrid Natalia Rojas-Galvis, Antonio Díaz-Caballero