Resumo
Introdução: a síndrome de Percherón é causada por lesões isquêmicas talâmicas bilaterais ocasionando uma série de anomalias clínicas como: alteração do estado de consciência, oftalmoplegia, e alterações da memória. Caso clínico: apresentamos o caso de uma mulher de 49 anos com diabetes mellitus, mau controle metabólico, episódios hipoglicêmicos e hiperglicêmicos repetitivos, que cursa com sintomatologia inespecífica, estudos imagiológicos não-invasivos documentados lesões talâmicas bilaterais. Conclusões: os quadros subagudos e isquêmicos parciais que envolvem a região paramediana do Tálamo bilateral poderiam ter alguma relação com episódios hipoglicêmicos e hiperglicêmicos repetitivos, que podem chegar a cursar com sintomatologia leve e inespecífica, o que o torna um desafio diagnóstico para a síndrome.
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