Abstract
Coronavirus disease 2019 (COVID-19) has generated a large-scale impact on global public health due to its rapid spread and its contagion, adaptation and evolution of high capacity. This review describes the differences between mutations, variants, lineages and strains of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); The main mutations present in the SARS-CoV-2 Variants Of Interest (VOI) and Variants Of Concern (VOC) and their geographic distribution are listed; and finally, the implication that new variants have on the vaccines effectiveness is analyzed, evidencing the importance of SARS-CoV-2 genomic surveillance in the post-vaccination era.
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